Recombinant Human Granulocyte Macrophage Colony Stimulating Factor

• Description:

  Recombinant Human Granulocyte Macrophage Colony Stimulating Factor

• Product Name Alternative:

  rHuGM-CSF

• Gene Name:

  CSF2

• UniProt:

  P04141

• Cellular Locus:

  Secreted

• Reactivity:

  Human

• Target Antigen:

  Granulocyte-macrophage colony-stimulating factor

• Target:

  Granulocyte Macrophage Colony Stimulating Factor

• Type:

  Protein

• Applications:

  WB

• Dilution:

  Reconstitute the lyophilized product in sterile water not less than 100 ug/ml. Product was dialyzed against 20mM sodium citrate pH 5 prior to lyophilization.

• Form:

  Lyophilized

• Function:

  Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. {PubMed:3925454}.

• Storage Conditions:

  Store lyophilized product desiccated below -18°C. After reconstitution, GM- CSF may be stored at 4°C for 2-7 days and below -18°C for future use. For long term storage, addition of 0.1% human serum albumin or bovine serum albumin is recommended. Avoid multiple freeze-thaw cycles.

• Specificity:

  Granulocyte Macrophage Colony Stimulating Factor

• Formulation:

  2mM sodium phosphate, pH 7.4.

• Buffer pH:

  pH 7.4

• Target Background:

  GM-CSF was first identified as a growth factor that supports in vitro colony formation of granulocyte-macrophage progenitor cells. It is produced in response to immune or inflammatory stimuli by activated T cells, B cells, macrophages, mast cells, fibroblasts, and alveolar epithelial cells. GM-CSF is a 22kDa protein, 144 amino acids, composed of four bundle alpha helices.

• CAS Number:

  9000-83-3