SingleFlowEx CD41 APC

SingleFlowEx CD41 APC

• Description: SingleFlowEx is fluorochrome-labeled monoclonal antibody single reagent for use in laboratory-developed multicolor flow cytometry tests in order to examine human clinical samples. SingleFlowEx can be used in various multicolor combinations. Laboratory shall establish the SingleFlowEx performance characteristics in conjunction with other reagents in normal and pathological samples.
• Certification: RUO, GMP
• Clone: MEM-06
• Validated Applications: FC
• Concentration: 0.040 mg/mL
• Format: APC
• Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
• Components: 1 vial of monoclonal antibody reagent. The content (1 mL) is sufficient for min. 100 Tests.
• References & Citations: *Belizaire RM, Prakash PS, Richter JR, Robinson BR, Edwards MJ, Caldwell CC, Lentsch AB, Pritts TA: Microparticles from stored red blood cells activate neutrophils and cause lung injury after hemorrhage and resuscitation. J Am Coll Surg. 2012 Apr214(4):648-55, URL: https://pubmed.ncbi.nlm.nih.gov/22342784/,*Pagani G, Pereira JPV, Stoldt VR, Beck A, Scharf RE, Gohlke H: The human platelet antigen-1b (Pro33) variant of 945IIb9463 allosterically shifts the dynamic conformational equilibrium of this integrin toward the active state. J Biol Chem. 2018 Mar 30293(13):4830-4844., URL: https://pubmed.ncbi.nlm.nih.gov/29462793/,*Use of this product has not been published., URL: ,
• Other References: *Mitjavila-Garcia MT, Cailleret M, Godin I, Nogueira MM, Cohen-Solal K, Schiavon V, Lecluse Y, Le Pesteur F, Lagrue AH, Vainchenker W: Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells. Development. 2002 Apr129(8):2003-13., URL: https://www.ncbi.nlm.nih.gov/pubmed/11934866?ordin,*Ferkowicz MJ, Starr M, Xie X, Li W, Johnson SA, Shelley WC, Morrison PR, Yoder MC: CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development. 2003 Sep130(18):4393-403., URL: https://www.ncbi.nlm.nih.gov/pubmed/12900455?ordin,*Zhang J, Varas F, Stadtfeld M, Heck S, Faust N, Graf T: CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation. Exp Hematol. 2007 Mar35(3):490-499., URL: https://www.ncbi.nlm.nih.gov/pubmed/17309829?ordin,*Debili N, Robin C, Schiavon V, Letestu R, Pflumio F, Mitjavila-Garcia MT, Coulombel L, Vainchenker W: Different expression of CD41 on human lymphoid and myeloid progenitors from adults and neonates. Blood. 2001 Apr 197(7):2023-30., URL: https://www.ncbi.nlm.nih.gov/pubmed/11264167?ordin,
• Storage Conditions: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.