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Napamezole

CAT: 0804-HY-105699Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105699Size:1 Each
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Description
Napamezole is an α2A adrenergic receptor antagonist and a serotonin/norepinephrine uptake inhibitor. Napamezole increases the levels of monoamines in the brain by blocking monoamine uptake, which gives it antidepressant activity[1].
CAS Number
91524-14-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/napamezole.html
Smiles
C1(CC2=NCCN2)=CC3=CC=CC=C3CC1
Molecular Formula
C14H16N2
Molecular Weight
212.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Cordi AA, et al. Potential antidepressants displayed combined alpha (2) -adrenoceptor antagonist and monoamine uptake inhibitor properties. J Med Chem. 2001 Mar 1;44 (5) :787-805.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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CatalogName
T28131-01Napamezole

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