Filamin

• NCBI Gene ID:

  2316

• Reactivity:

  Chicken, Guinea Pig, Human, Mouse, Rabbit, Rat

• Storage Conditions:

  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

• Specificity:

  Recognizes native, full-length human filamin (actin-binding protein) at 270-280kD and the 190kD N-terminal calpain cleavage fragment of filamin. Following induction of apoptosis in U937 cells, the antibody recognizes 170, 150, and 120kD N-terminal cleavage fragments of the full-length form presumably resulting from cleavage by activated caspase-3. Species Crossreactivity: chicken, guniea pig, mouse, rabbit and rat

• Other Gene Names:

  [FLNA; FLNA; FLN; FMD; MNS; OPD; ABPX; CSBS; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280; FLN; FLN1; FLN-A; ABP-280]

• Short Name:

  [Filamin]

• Other Product Names:

  [filamin-A isoform 2; Filamin-A; filamin-A; filamin-1; alpha-filamin; non-muscle filamin; actin binding protein 280; endothelial actin-binding protein; filamin A, alpha; Actin-binding protein 280; ABP-280; Alpha-filamin; Endothelial actin-binding protein; Filamin-1; Non-muscle filamin]

• NCBI GI Number:

  160420317

• NCBI Accession Number:

  NP_001104026.1

• NCBI GB Accession Number:

  NM_001110556.1

• Uniprot Accession Number:

  P21333