Cetirizine-d4
CAT:
804-HY-17042S-03
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cetirizine-d4
- CAS Number: 1219803-84-5
- UNSPSC Description: Cetirizine-d4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
- Target Antigen: Histamine Receptor
- Type: Isotope-Labeled Compounds
- Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Solubility: 10 mM in H2O
- Smiles: O=C(O)COC([2H])([2H])C([2H])([2H])N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1
- Molecular Weight: 392.91
- References & Citations: [1]Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055•1080, 1993.|[2]Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5.|[3]Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported