Apaf-1 (Apoptosis Protease Activating Factor 1) (Biotin)

Apaf-1 (Apoptosis Protease Activating Factor 1) (Biotin)

• Gene Name: [Apaf-1]
• Reactivity: Human, C. elegans, Mammalian, Mouse
• Storage Conditions: Store at -20 degree C.
• Specificity: Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. Recognizes a 130kD band in Western blots. Species Crossreactivity: Human, mouse
• Short Name: [Apaf-1]