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Defoslimod

CAT: 0804-HY-164386Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164386Size:1 Each
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Description
Defoslimod (OM 174) is an agonist for TLR4 receptor and acts as an immunomodulator. Defoslimod activates macrophages and dendritic cells, induces cytokines secretion, and exhibits antitumor efficacy in rats[1].
CAS Number
171092-39-0
Product Name Alternative
OM 174
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/defoslimod.html
Smiles
O=P(O)(O)O[C@H]([C@@H]([C@H]([C@@H]1O)O)NC(C[C@H](O)CCCCCCCCCCC)=O)O[C@@H]1CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(O)(O)=O)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O
Molecular Formula
C52H100N2O20P2
Molecular Weight
1135.30
References & Citations
[1]Isambert N, et al., Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors. BMC Cancer. 2013 Apr 2;13:172.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

Alternative Products

CatalogName
GTR19238077-01Defoslimod

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