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Niloticin

CAT: 0804-HY-N3188-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3188-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Niloticin, tetracyclic triterpenoid compound, is a osteoclastogenesis inhibitor. Niloticin shows anti-viral, antioxidative, and mosquitocidal activities. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways[1].
CAS Number
115404-57-4
UNSPSC
12352005
Target
Akt; NF-κB
Type
Natural Products
Related Pathways
NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/niloticin.html
Purity
98.0
Solubility
Acetone : ≥ 25 mg/mL
Smiles
C[C@@]1(CC[C@@]2([H])[C@@H](C)C[C@H]([C@@](O3)([H])C3(C)C)O)C([C@]4([H])CC[C@]12C)=CC[C@](C(C)5C)([H])[C@@]4(CCC5=O)C
Molecular Formula
C30H48O3
Molecular Weight
456.70
References & Citations
[1]Xu H, et al. Niloticin inhibits osteoclastogenesis by blocking RANKL-RANK interaction and suppressing the AKT, MAPK, and NF-κB signaling pathways. Biomed Pharmacother. 2022 May;149:112902.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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