Sar-Arg-Val-Tyr-Val-His-NH2

Sar-Arg-Val-Tyr-Val-His-NH2

• CAS Number: 2410957-04-7
• UNSPSC Description: Sar-Arg-Val-Tyr-Val-His-NH2 is a Gq-biased agonists, exhibits 10-fold larger molecular efficacies at the AT1R-Gq fusion protein compared with the AT1R-βarr2 fusion protein[1].
• Target Antigen: Others
• Type: Peptides
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/trv120055.html
• Purity: 96.63
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](C(C)C)C(N[C@@H](CC2=CNC=N2)C(N)=O)=O)=O)=O)=O)CNC
• Molecular Weight: 742.87
• References & Citations: [1]Strachan RT, et, al. Divergent transducer-specific molecular efficacies generate biased agonism at a G protein-coupled receptor (GPCR). J Biol Chem. 2014 May 16; 289(20): 14211-24.|[2]Rajagopal S, et, al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol. 2011 Sep;80(3):367-77.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported