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Antineoplaston A10

CAT: 0804-HY-128553-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-128553-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antineoplaston A10 is an antineoplaston that inhibits the growth of human hepatoma cells by inducing apoptosis. Antineoplaston A10 can be used in the study of liver cancer and breast cancer[1][2].
CAS Number
91531-30-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Bcl-2 Family; Endogenous Metabolite; MDM-2/p53
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antineoplaston-a10.html
Purity
99.84
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC1)C(NC1=O)=O)CC2=CC=CC=C2
Molecular Formula
C13H14N2O3
Molecular Weight
246.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Qu XJ, et al. Induction of apoptosis in human hepatocellular carcinoma cells by synthetic antineoplaston A10. Anticancer Res. 2007 Jul-Aug;27 (4B) :2427-31.|[2]Tsuda, et al. "Inhibitory effect of antineoplaston A-10 on breast cancer transplanted to athymic mice and human hepatocellular carcinoma cell lines." The Kurume Medical Journal 37.2 (1990) : 97-104.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported