Adenosine 2',5'-diphosphate (sodium)

• UNSPSC Description:

  Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors[1][2].

• Target Antigen:

  Endogenous Metabolite; P2Y Receptor

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/adenosine-2-5-diphosphate-sodium.html

• Purity:

  99.0

• Solubility:

  H2O : 50 mg/mL (ultrasonic;warming)

• Smiles:

  O=[P](O)(O)O[C@H]([C@@H]1O)[C@@](N2C3=NC=NC(N)=C3N=C2)([H])O[C@@H]1CO[P](O)(O)=O.[x].[Na]

• References & Citations:

  [1]Boyer JL, et al. Identification of competitive antagonists of the P2Y1 receptor. Mol Pharmacol. 1996;50(5):1323-1329.|[2]Toth-Zsamboki E, et al. The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel. Thromb Haemost. 2001;86(5):1338-1339.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  154146-84-6