BIRC5, Human

CAT: 0804-HY-P7645-01Size: 10 µgDry Ice: NoHazardous: No
CAT#:0804-HY-P7645-01Size:10 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BIRC5 Protein, Human, a protein in the intrinsic apoptotic pathway that interacts with XIAP and DIABLO leading to caspase-3 and caspase-9 inactivation. BIRC5 (survivin) is also involved in stabilizing the microtubule-kinetochore dynamics[1].
Product Name Alternative
BIRC5 Protein, Human, Human, E. coli
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/birc5-protein-human.html
Purity
97.76
Smiles
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAMD
Molecular Formula
332 (Gene_ID) O15392-1 (M1-D142) (Accession)
Molecular Weight
16-18 kDa
References & Citations
[1]Fieke Lamers, et al. Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe. Endocr Relat Cancer. 2011 Oct 27;18 (6) :657-68.|[2]J Hagenbuchner, et al. BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery. Oncogene. 2013 Oct;32 (40) :4748-57.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins

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