DFHBI-1T

DFHBI-1T

• CAS Number: 1539318-36-9
• UNSPSC Description: DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells[1][2].
• Target Antigen: DNA Stain
• Type: Dye Reagents
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/dfhbi-1t.html
• Purity: 98.12
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C1N(CC(F)(F)F)C(C)=N/C1=C\C2=CC(F)=C(O)C(F)=C2
• Molecular Weight: 320.21
• References & Citations: [1]Wenjiao Song, et al. Plug-and-play fluorophores extend the spectral properties of Spinach. J Am Chem Soc. 2014 Jan 29;136(4):1198-201.|[2]Grigory S Filonov, et al. Broccoli: rapid selection of an RNA mimic of green fluorescent protein by fluorescence-based selection and directed evolution. J Am Chem Soc. 2014 Nov 19;136(46):16299-308.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: No Development Reported