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Cholestyramine

CAT: 0804-HY-104081-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-104081-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cholestyramine (Colestyramine) is a bile acid binding resin and can inhibit intestinal bile acid absorption which results in the increasing bile acid synthesis from cholesterol.
CAS Number
11041-12-6
Product Name Alternative
Cholestyramine resin; Colestyramine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Colestyramine.html
Solubility
1 M HCl : < 1 mg/mL (ultrasonic; adjust pH to 1 with HCl) |DMSO : < 1 mg/mL|H2O : < 0.1 mg/mL
Smiles
C[N+](C)(C)CC1=CC=C(C(CC(C)C2=CC=CC=C2)CC)C=C1.CC(CC)C.[Cl-].[n]
Precautions
H302, H315, H319, H335
References & Citations
[1]Maugeais C, et al. rHDL administration increases reverse cholesterol transport in mice, but is not additive on top of ezetimibe or cholestyramine treatment. Atherosclerosis. 2013 Jul;229 (1) :94-101.|[2]Rebecca M. Heidker, et al. Grape Seed Procyanidins and Cholestyramine Differentially Alter Bile Acid and Cholesterol Homeostatic Gene Expression in Mouse Intestine and Liver. PLoS One. 2016; 11 (4) : e0154305.|[3]J M Pruckler, et al. Use of a human microvascular endothelial cell line as a model system to evaluate cholesterol uptake. Pathobiology. 1993;61 (5-6) :283-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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