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IKKβ (phospho-Y199) polyclonal antibody

CAT: 0013-GTR18042897-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18042897-01Size:25 µL
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Description
Rabbit polyclonal antibody to IKK beta (phospho-Y199)
Product Name Alternative
Inhibitor of nuclear factor kappa B kinase beta subunit; I-kappa-B-kinase beta; IkBKB; IKK-B; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
UniProt
O14920
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human eEF2K around the phosphorylation site of Tyrosine 199.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
IHC-P: 1:50-1:200
Form
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
~ 86 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC
Host or Source
Rabbit
Preservative
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · O14920

Inhibitor of nuclear factor kappa-B kinase subunit beta

IKKB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O14920
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IKBKB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
I-kappa-B-kinase beta, IKK-B, IKK-beta, IkBKB
EC number
2.7.11.10
Processing
—
Secondary accessions
B4DZ30, B4E0U4, O75327
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationHydroxylationIsopeptide bondPhosphoproteinS-nitrosylationUbl conjugation

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmMembraneNucleus

Disease

Disease variantSCID

Biological process

Host-virus interaction

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

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