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Chk2 (phospho-T68) polyclonal antibody

CAT: 0013-GTR18042694-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18042694-01Size:25 µL
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Description
Rabbit polyclonal antibody to Chk2 (phospho-T68)
Product Name Alternative
Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2; CHEK2; CDS1; CHK2; RAD53
UniProt
O96017
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human Chk2 around the phosphorylation site of Threonine 68.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB: 1:500-1:1000, IHC-P: 1:50-1:200
Form
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
~ 62 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, WB
Host or Source
Rabbit
Preservative
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · O96017

Serine/threonine-protein kinase Chk2

CHK2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O96017
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHEK2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A8K3Y9, B7ZBF3, B7ZBF4, B7ZBF5, Q6QA03, Q6QA04, Q6QA05, Q6QA06, Q6QA07, Q6QA08, Q6QA10, Q6QA11, Q6QA12, Q6QA13, Q9HBS5, Q9HCQ8, Q9UGF0, Q9UGF1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCell cycleCell divisionDNA damageDNA repairHost-virus interactionMitosisTranscriptionTranscription regulation

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Disease

Disease variantLi-Fraumeni syndromeTumor suppressor

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

Cellular component

Nucleus

PTM

PhosphoproteinUbl conjugation

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