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MEK1 (T286) polyclonal antibody

CAT: 0013-GTR18042868-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18042868-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal antibody to MEK1 (T286)
Product Name Alternative
Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K1; MEK-1; PRKMK1
UniProt
Q02750
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 260-310 of Human MEK1.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB: 1:500-1:1000, IHC-P: 1:50-1:200
Form
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
~ 45 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC, WB
Host or Source
Rabbit
Preservative
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · Q02750

Dual specificity mitogen-activated protein kinase kinase 1

MP2K1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02750
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP2K1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MAP kinase kinase 1, MAPKK 1, MKK1
EC number
2.7.12.2
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Disease

CardiomyopathyDisease variantEctodermal dysplasiaIntellectual disability

Cellular component

CytoplasmCytoskeletonMembraneNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferaseTyrosine-protein kinase

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