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BPiDDB

CAT: 0804-HY-107674-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107674-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BPiDDB is a potent nAChR antagonist. bPiDDB potently (IC50=2 nM) inhibits nicotine-evoked striatal dopamine (DA) release through an interaction with α6β2-containing nAChRs[1].
CAS Number
525596-66-1
UNSPSC
12352005
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bpiddb.html
Purity
99.35
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=C[N+](CCCCCCCCCCCC[N+]2=CC=CC(C)=C2)=CC=C1.[Br-].[Br-]
Molecular Formula
C24H38Br2N2
Molecular Weight
514.38
References & Citations
[1]Smith AM, et al. Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release. Biochem Pharmacol. 2010 Aug 1;80 (3) :402-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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