ent-Florfenicol-d3

ent-Florfenicol-d3

• CAS Number: 1217619-10-7
• UNSPSC Description: ent-Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for the treatment of bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.
• Target Antigen: Antibiotic; Bacterial
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection
• Field of Research: Infection
• Solubility: 10 mM in DMSO
• Smiles: [C@@H]([C@](NC(C(Cl)Cl)=O)(C(F)([2H])[2H])[2H])(O)C1=CC=C(S(C)(=O)=O)C=C1
• Molecular Weight: 361.23
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Al-Shahrani S, et al. Florfenicol induces early embryonic death in eggs collected from treated hens. BMC Vet Res. 2015 Aug 18;11(1):213.|[3]Corinna Kehrenberg, et al. A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503. Molecular Microbiology
 Volume 57, Issue 4, pages 1064–1073, August 2005
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported