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Ku-70 (R586) polyclonal antibody

CAT: 0013-GTR18041300-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18041300-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal antibody to Ku-70 (R586)
Product Name Alternative
X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in; Chinese hamster cells 6; XRCC6; G22P1
UniProt
P12956
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 560-600 of Human Ku-70.
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer, DNA Damage, Epigenetics, Immunology, Infectious Diseases
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
IHC-P: 1:50-1:200
Form
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
~ 70 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC
Host or Source
Rabbit
Preservative
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · P12956

DNA repair protein Ku70

XRCC6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12956
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
XRCC6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.2.99.18, 5.6.2.4
Processing
—
Secondary accessions
B1AHC8, Q6FG89, Q9UCQ2, Q9UCQ3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationADP-ribosylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingHelicaseHydrolaseIsomeraseLyaseMultifunctional enzyme

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

ChromosomeCytoplasmNucleus

Biological process

DNA damageDNA recombinationDNA repairHost-virus interactionImmunityInnate immunityTranscriptionTranscription regulation

Disease

Systemic lupus erythematosus

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