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Detajmium

CAT: 0804-HY-115839Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115839Size:1 Each
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Description
Detajmium (Tachmalcor free base) is a Na-channel blocker with activity to inhibit ventricular conduction and refractoriness. Detajmium (0.3μM) prolongs intraventricular conduction time comparable to propafenone (0.3μM) during sinus rhythm, but the time constant for reaching steady state during rapid ventricular pacing is significantly longer for Detajmium, indicating a unique temporal profile for its heart rate-dependent effects.
CAS Number
47719-70-0
Product Name Alternative
Tachmalcor (free base)
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/detajmium.html
Smiles
OC1[C@]23[C@](N(C4=CC=CC=C43)C)([H])[C@@]5([H])[N+]6([C@@]([C@]1([H])[C@@]([C@@H]([C@H]6O)CC)([H])C5)([H])C2)CC(O)CN(CC)CC
Molecular Formula
C27H42N3O3+
Molecular Weight
456.64
References & Citations
[1]Rate-dependent effects of detajmium and propafenone on ventricular conduction and refractoriness in isolated guinea pig hearts
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
T25312-01Detajmium
GTR19199313-01Detajmium bitartrate

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