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2-Bromoestradiol

CAT: 0804-HY-137391-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137391-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Bromoestradiol is a estrogen 2-hydroxylase inhibitor. 2-Bromoestradiol decreases irreversible binding of radiolabeled estradiol metabolite (s) to microsomal proteins[1].
CAS Number
15833-07-5
UNSPSC
12352005
Hazard Statement
H302, H312, H332, H350, H360
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-bromoestradiol.html
Purity
99.59
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=C(Br)C(O)=C4)[C@@]3([H])CC2
Molecular Formula
C18H23BrO2
Molecular Weight
351.28
Precautions
H302, H312, H332, H350, H360
References & Citations
[1]Brueggemeier RW, et al. Estrogen metabolism in rat liver microsomal and isolated hepatocyte preparations--II. Inhibition studies. J Steroid Biochem. 1984 Dec;21 (6) :709-16.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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