DNMT1 polyclonal antibody

CAT: 0013-GTR18040191-02Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0013-GTR18040191-02Size:100 µL

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Description

Rabbit polyclonal antibody to Dnmt1

Product Name Alternative

Anti-ADCADN antibody, anti- AIM antibody, anti- CXXC finger protein 9 antibody, anti- CXXC-type zinc finger protein 9 antibody, anti- CXXC9 antibody, anti- DNA (cytosine 5) methyltransferase 1 antibody, anti- DNA (cytosine-5) -methyltransferase 1 antibody, anti- DNA methyltransferase 1 antibody, anti- DNA methyltransferase HsaI antibody, anti- DNA methyltransferase M.HsaI. antibody, anti- DNA MTase antibody, anti- DNA MTase HsaI antibody, anti- DNMT 1 antibody, anti- DNMT antibody, anti- Dnmt1 antibody, anti- Dnmt1 antibody, anti- DNMT1_HUMAN antibody, anti- Dnmt1o antibody, anti- FLJ16293 antibody, anti- HSN1E antibody, anti- M.HsaI antibody, anti- MCMT antibody, anti- Met1 antibody, anti- MGC104992 antibody, anti- mMmul antibody, anti- MommeD2 antibody, anti-antibody

UniProt

P26358

Reactivity

Human

Immunogen

Recombinant fusion protein of human DNMT1 (NP_001370.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1mg/ml

Dilution

WB1:500 - 1:2000, IHC-P: -P1:50 - 1:200, IF1:50 - 1:200IP1:50 - 1:100

Form

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

Molecular Weight

200kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IF, IP, WB

Host or Source

Rabbit

Preservative

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · P26358

DNA (cytosine-5)-methyltransferase 1

DNMT1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P26358
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: DNMT1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Dnmt1
EC number: 2.1.1.37
Processing: —
Secondary accessions: A0AV63, B7ZLW6, Q9UHG5, Q9ULA2, Q9UMZ6

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorChromatin regulatorDNA-bindingMethyltransferaseRepressorTransferase

Coding sequence diversity

Alternative splicing

Cellular component

ChromosomeNucleus

Disease

DeafnessDisease variantNeuropathy

Ligand

Metal-bindingS-adenosyl-L-methionineZinc

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

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