Interleukin-5 (Human, Recombinant)

• Description:

  Interleukin-5 (Human, Recombinant)_x000D_ Catalog number: B2010312_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Interleukin-5 (Human, Recombinant) expressed in CHO. This protein acts as a selective activator of human eosinophil function._x000D_ Storage: -20C_x000D_ Keywords: rHuIL-5; EDF; BCDFII; TRF_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Bagnasco D, Ferrando M, Caminati M, Bragantini A, Puggioni F, Varricchi G,_x000D_ Passalacqua G, Canonica GW. Targeting Interleukin-5 or Interleukin-5Rα: Safety_x000D_ Considerations. Drug Saf. 2017 Jul;40(7):559-570._x000D_ _x000D_ 2: Poblete MJ, Rosenbaum A, Winter M. Anti-interleukin 5 therapy for chronic_x000D_ rhinosinusitis with polyps. Medwave. 2018 Oct 24;18(6):e7301. Spanish, English._x000D_ _x000D_ 3: Takatsu K. Interleukin-5 and IL-5 receptor in health and diseases. Proc Jpn_x000D_ Acad Ser B Phys Biol Sci. 2011;87(8):463-85._x000D_ _x000D_ 4: Giannetti MP, Cardet JC. Interleukin-5 Antagonists Usher in a New Generation_x000D_ of Asthma Therapy. Curr Allergy Asthma Rep. 2016 Nov;16(11):80._x000D_ _x000D_ 5: Kay AB, Klion AD. Anti-interleukin-5 therapy for asthma and hypereosinophilic_x000D_ syndrome. Immunol Allergy Clin North Am. 2004 Nov;24(4):645-66, vii._x000D_ _x000D_ 6: Boggu PR, Kim Y, Jung SH. Discovery of benzimidazole analogs as a novel_x000D_ interleukin 5 inhibitors. Eur J Med Chem. 2019 Nov 1;181:111574._x000D_ _x000D_ 7: Corren J. Inhibition of interleukin 5 for the treatment of eosinophilic_x000D_ diseases. Discov Med. 2012 Apr;13(71):305-12._x000D_ _x000D_ 8: Roboz GJ, Rafii S. Interleukin 5 and the regulation of eosinophil production._x000D_ Curr Opin Hematol. 1999 May;6(3):164-8._x000D_ _x000D_ 9: Karlen S, Mordvinov VA, Sanderson CJ. How is expression of the interleukin 5_x000D_ gene regulated? Immunol Cell Biol. 1996 Apr;74(2):218-23._x000D_ 10: Miyazaki J, Takaki S, Araki K, Tashiro F, Tominaga A, Takatsu K, Yamamura K._x000D_ Expression vector system based on the chicken beta-actin promoter directs_x000D_ efficient production of interleukin-5. Gene. 1989 Jul 15;79(2):269-77._x000D_ _x000D_ Products Related to Interleukin-5 (Human, Recombinant) : Proteins

• Short Description:

  Catalog Number: B2010312 (10 ug)_x000D_ Interleukin-5 (Human, Recombinant) is a high quality research product used as highly pure Interleukin-5 (Human, Recombinant) expressed in CHO. This protein acts as a selective activator of human eosinophil function. Custom bulk orders of this product are available upon request.

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3