Fibronectin

• UNSPSC Description:

  Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans[1].

• Target Antigen:

  Integrin

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Cytoskeleton

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/fibronectin.html

• Purity:

  97.0

• Solubility:

  H2O : 8.33 mg/mL (ultrasonic;adjust pH to 7 with NaOH)

• Smiles:

  [Fibronectin]

• References & Citations:

  [1]Yuan-Wan Sun, et al. Effects of E-Cigarette Aerosols with Varying Levels of Nicotine on Biomarkers of Oxidative Stress and Inflammation in Mice. Chem Res Toxicol. 2021 Apr 19;34(4):1161-1168.|[2]Roumen Pankov, et al. Fibronectin at a glance. J Cell Sci. 2002 Oct 15;115(Pt 20):3861-3.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  Phase 3

• CAS Number:

  86088-83-7