Budipine

CAT: 0804-HY-W001601-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-W001601-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Budipine is an anti-parkinson agent. Budipine also is a substrate of P-glycoprotein (P-gp), is mediated the uptake into the brain by P-gp. Budipine also is N-methyl-d-aspartate (NMDA) antagonist, and has indirect dopaminergic effects through an improved dopamine release, the inhibition of monoamine oxidase type B (MAO-B) . Budipine can be used for the research of CNS disorders include Parkinson disease[1].

CAS Number

57982-78-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Budipine.html

Concentration

10mM

Purity

99.41

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC(N1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)CC1)(C)C

Molecular Formula

C21H27N

Molecular Weight

293.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Manfred Uhr, et al. The anti-Parkinson drug budipine is exported actively out of the brain by P-glycoprotein in mice. Neurosci Lett. 2005 Jul 22-29;383 (1-2) :73-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

NMDA Receptor

Alternative Products

Catalog	Name
BA6765-50	Budipine
FB172928-01	Budipine hydrochloride

Budipine

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