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BemPPOX

CAT: 0804-HY-114754Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-114754Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BemPPOX is an orally active, potent dog gastric lipase (DGL) inhibitor with Xl50 (the inhibitor molar excess leading to 50% lipase inhibition) of 0.5. BemPPOX is also a good inhibitor of GPLRP2 (xl50=0.64) . BemPPOX efficiently regulates the gastrointestinal lipolysis and slows down the overall lipolysis process in rats. BemPPOX has the potential for obesity research[1].
CAS Number
1998101-23-7
UNSPSC
12352005
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bemppox.html
Smiles
O=C1OC(OCCOCC2=CC=CC=C2)=NN1C3=CC=CC(OC4=CC=CC=C4)=C3
Molecular Formula
C23H20N2O5
Molecular Weight
404.42
References & Citations
[1]Vanessa Point, et al. Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis. Eur J Med Chem. 2016 Nov 10:123:834-848.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T26766-01BemPPOX

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