ADC Control Human IgG1-Deruxtecan (DAR 8)
CAT:
804-HY-164152A-02
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: Yes
ADC Control Human IgG1-Deruxtecan (DAR 8)
- UNSPSC Description: ADC Control Human IgG1-Deruxtecan (DAR 8) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E)[1].
- Target Antigen: Antibody-Drug Conjugates (ADCs); Topoisomerase
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/adc-control-human-igg1-deruxtecan-dar-8.html
- Smiles: [ADC Control Human IgG1-Deruxtecan (DAR 8)]
- References & Citations: [1]Matilde Bocci, et al. In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment. J Control Release. 2024 Mar:367:779-790.
- Shipping Conditions: Dry Ice
- Clinical Information: No Development Reported