Copanlisib (Standard)

CAT: 0804-HY-15346R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15346R-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Copanlisib (Standard) is the analytical standard of Copanlisib. This product is intended for research and analytical applications. Copanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity[1].
CAS Number
[1032568-63-0]
Product Name Alternative
BAY 80-6946 (Standard)
UNSPSC
12352005
Target
Apoptosis; PI3K; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/copanlisib-standard.html
Smiles
O=C(C1=CN=C(N)N=C1)NC2=NC3=C(OC)C(OCCCN4CCOCC4)=CC=C3C5=NCCN25
Molecular Formula
C23H28N8O4
Molecular Weight
480.52
References & Citations
[1]Liu N, et al. BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models. Mol Cancer Ther. 2013 Nov;12 (11) :2319-30.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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