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RNASEH2A Rabbit Polyclonal Antibody

CAT: 0013-GTR18037096-02Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18037096-02Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes
Product Name Alternative
RNASEHI, RNHIA
UniProt
O75792
Reactivity
Human
Immunogen
Ribonuclease H2, subunit A
Target
RNASEH2A
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, IHC, IP, WB
Host or Source
Rabbit
Isotype
IgG

UniProtKB · O75792

Ribonuclease H2 subunit A

RNH2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75792
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RNASEH2A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
RNase H2 subunit A
EC number
3.1.26.4
Processing
—
Secondary accessions
B2RCY1, Q96F11
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Disease

Aicardi-Goutieres syndromeDisease variant

Molecular function

EndonucleaseHydrolaseNuclease

Ligand

Metal-binding

Cellular component

Nucleus

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