Anticancer agent 73

Anticancer agent 73

• CAS Number: 9007-83-4
• UNSPSC Description: Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo[1].
• Target Antigen: DNA/RNA Synthesis
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/anticancer-agent-73.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1=C(C)OC(C2=CC=C(OC)C=C2)=N1)OCC
• Molecular Weight: 261.27
• References & Citations: [1]Peng T, et al. Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis. J Med Chem. 2022 Jun 13.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported