Boc-Asp(OBzl)-CMK

• UNSPSC Description:

  Boc-Asp(OBzl)-CMK is an inhibitor for IL-1 converting enzyme (ICE, caspase1). Boc-Asp(OBzl)-CMK prevents death of CHP100 neuroblastoma cell, and IL-1β release elicited by the viral coat protein[1].

• Target Antigen:

  Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/boc-asp-obzl-cmk.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OCC1=CC=CC=C1)C[C@@H](C(CCl)=O)NC(OC(C)(C)C)=O

• Molecular Weight:

  355.81

• References & Citations:

  [1]Corasaniti MT, et al., HIV-1 coat protein gp120 stimulates interleukin-1beta secretion from human neuroblastoma cells: evidence for a role in the mechanism of cell death. Br J Pharmacol. 2001 Nov;134(6):1344-50.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  172702-58-8