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HYL001

CAT: 0804-HY-160237-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-160237-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HYL001 (compund 338) is a potent inhibitor of TGFβ receptor 1 (ALK5) that is approximately 9 times more potent than the structurally related compound Galunisertib and is able to eliminate liver metastases established in mice[1].
CAS Number
2426547-83-1
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hyl001.html
Purity
99.94
Solubility
DMSO : 17.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC1=CC2=C(C3=C(CCC4)N4N=C3C5=CC=CC(C)=N5)C=CN=C2C=C1
Molecular Formula
C21H18N4O
Molecular Weight
342.39
References & Citations
[1]WO2020104648
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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