Kindlin-1/KIND1

• Gene Name:

  [FERMT1]

• NCBI Gene ID:

  55612

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8°C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining.

• Other Gene Names:

  [FERMT1; FERMT1; URP1; KIND1; DTGCU2; UNC112A; C20orf42; C20orf42; KIND1; URP1]

• Short Name:

  [Kindlin-1/KIND1]

• Other Product Names:

  [fermitin family homolog 1; Fermitin family homolog 1; fermitin family homolog 1; fermitin family member 1; Kindlerin; Kindlin syndrome protein; Kindlin-1; Unc-112-related protein 1]

• NCBI GI Number:

  116686114

• NCBI Accession Number:

  NP_060141.3

• NCBI GB Accession Number:

  NP_060141.3

• Uniprot Accession Number:

  Q9BQL6