Myelin Basic Protein

• Gene Name:

  [MBP]

• NCBI Gene ID:

  4155

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30% of the total protein and about 10% of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin. MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas.

• Other Gene Names:

  [MBP; MBP; MBP]

• Short Name:

  [Myelin Basic Protein]

• Other Product Names:

  [myelin basic protein; Myelin basic protein; myelin basic protein; Golli-MBP; proline-rich proteoglycan 2; myelin basic protein; Myelin A1 protein; Myelin membrane encephalitogenic protein]

• NCBI GI Number:

  1162922

• NCBI Accession Number:

  AAC41944.1

• Uniprot Accession Number:

  P02686