FLI1 (Ewing's Sarcoma Endothelial Marker)

FLI1 (Ewing's Sarcoma Endothelial Marker)

• Gene Name: [FLI1]
• NCBI Gene ID: 2313
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a protein of 51kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewings Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
• Other Gene Names: [FLI1; FLI1; EWSR2; SIC-1; BDPLT21]
• Short Name: [FLI1]
• Other Product Names: [Friend leukemia integration 1 transcription factor isoform 2; Friend leukemia integration 1 transcription factor; Friend leukemia integration 1 transcription factor; Fli-1 proto-oncogene, ETS transcription factor; Proto-oncogene Fli-1; Transcription factor ERGB]
• NCBI GI Number: 264681554
• NCBI Accession Number: NP_001161153.1
• NCBI GB Accession Number: NP_001161153.1
• Uniprot Accession Number: Q01543