FLI1 (Ewing's Sarcoma Endothelial Marker)

• Gene Name:

  [FLI1]

• NCBI Gene ID:

  2313

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 51kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewings Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

• Other Gene Names:

  [FLI1; FLI1; EWSR2; SIC-1; BDPLT21]

• Short Name:

  [FLI1]

• Other Product Names:

  [Friend leukemia integration 1 transcription factor isoform 2; Friend leukemia integration 1 transcription factor; Friend leukemia integration 1 transcription factor; Fli-1 proto-oncogene, ETS transcription factor; Proto-oncogene Fli-1; Transcription factor ERGB]

• NCBI GI Number:

  264681554

• NCBI Accession Number:

  NP_001161153.1

• NCBI GB Accession Number:

  NP_001161153.1

• Uniprot Accession Number:

  Q01543