Nidogen/Entactin

Nidogen/Entactin

• Gene Name: [NID-1]
• NCBI Gene ID: 18073
• Reactivity: Guinea Pig, Mouse
  Does not react with Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: It reacts with the intact (150kDa) nidogen as well as its proteolytic fragments of 135kDa, 110kDa, 100kDa, and 80kDa. This MAb does not cross-react with other basement membrane components or fibronectin. Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation.
• Other Gene Names: [Nid1; Nid1; Nid; entactin; nidogen-1; A630025O17; entactin-1; Ent; NID-1]
• Short Name: [Nidogen/Entactin]
• Other Product Names: [nidogen-1; Nidogen-1; nidogen-1; nidogen 1; Entactin]
• NCBI GI Number: 171543883
• NCBI Accession Number: NP_035047.2
• NCBI GB Accession Number: NP_035047.2
• Uniprot Accession Number: P10493