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CD162 (Selectin P Ligand)

CAT: 0544-MBS4381560-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
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CAT#:0544-MBS4381560-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[SELPLG]
NCBI Gene ID
6404
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
Other Gene Names
[SELPLG; SELPLG; CLA; CD162; PSGL1; PSGL-1; PSGL-1]
Short Name
[CD162]
Other Product Names
[P-selectin glycoprotein ligand 1 isoform 1; P-selectin glycoprotein ligand 1; P-selectin glycoprotein ligand 1; selectin P ligand; Selectin P ligand]
NCBI GI Number
331284238
NCBI Accession Number
NP_001193538.1
NCBI GB Accession Number
NP_001193538.1
Uniprot Accession Number
Q14242

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