CD40, Mouse

• Gene Name:

  [CD40]

• NCBI Gene ID:

  21939

• Reactivity:

  Mouse
  Does not react with Human.

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.

• Other Gene Names:

  [Cd40; Cd40; IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936; Tnfrsf5]

• Short Name:

  [CD40]

• Other Product Names:

  [Tumor necrosis factor receptor superfamily member 5; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40 antigen; B-cell surface antigen CD40; Bp50; CD40L receptor; CD_antigen: CD40]

• NCBI GI Number:

  172046819

• NCBI Accession Number:

  P27512.3

• Uniprot Accession Number:

  P27512