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CD40, Mouse

CAT: 0544-MBS4381532-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381532-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CD40]
NCBI Gene ID
21939
Reactivity
Mouse
Does not react with Human.
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.
Other Gene Names
[Cd40; Cd40; IGM; p50; Bp50; GP39; IMD3; TRAP; HIGM1; T-BAM; Tnfrsf5; AI326936; Tnfrsf5]
Short Name
[CD40]
Other Product Names
[Tumor necrosis factor receptor superfamily member 5; Tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily member 5; CD40 antigen; B-cell surface antigen CD40; Bp50; CD40L receptor; CD_antigen: CD40]
NCBI GI Number
172046819
NCBI Accession Number
P27512.3
Uniprot Accession Number
P27512

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