MECA-79

CAT: 0544-MBS4381526-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381526-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[MECA-79]
Reactivity
Human, Mouse, Rat
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 beta1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissues. MECA-79 antibody reacts with Mouse, human and many other species PNAd and blocks L-selectin-dependent lymphocyte adhesion in vitro and in vivo.
Short Name
[MECA-79]

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Alternative Products

CatalogName
sc-19602MECA-79 (MECA-79)
sc-19602 HRPMECA-79 (MECA-79) HRP
sc-19602 FITCMECA-79 (MECA-79) FITC
sc-19602 ACMECA-79 (MECA-79) AC
sc-19602 LMECA-79 (MECA-79) L
sc-19602 PEMECA-79 (MECA-79) PE
BNUM1599-50MECA-79 (MECA-79), 1mg/mL
BNUB1599-100MECA-79 (MECA-79), 0.2mg/mL
sc-19602 AF488MECA-79 (MECA-79) Alexa Fluor® 488
sc-19602 AF647MECA-79 (MECA-79) Alexa Fluor® 647

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