CD19 (B-Lymphocyte Marker)

CD19 (B-Lymphocyte Marker)

• Gene Name: [CD19]
• NCBI Gene ID: 930
• Reactivity: Human
• Storage Conditions: Antibody without azide - store at -20 to -80 degrees C. Non-hazardous. No MSDS required.
• Specificity: CD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms.
• Other Gene Names: [CD19; CD19; B4; CVID3]
• Short Name: [CD19]
• Other Product Names: [B-lymphocyte antigen CD19 isoform 1; B-lymphocyte antigen CD19; B-lymphocyte antigen CD19; CD19 molecule; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12]
• NCBI GI Number: 296010921
• NCBI Accession Number: NP_001171569.1
• NCBI GB Accession Number: NP_001171569.1
• Uniprot Accession Number: P15391