RCAS1/Estrogen Receptor Binding Site Associated, Antigen 9

RCAS1/Estrogen Receptor Binding Site Associated, Antigen 9

• CAS Number: 9007-83-4
• Gene Name: [EBAG9]
• NCBI Gene ID: 9166
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
• Other Gene Names: [EBAG9; EBAG9; EB9; PDAF; RCAS1]
• Short Name: [RCAS1/Estrogen Receptor Binding Site Associated, Antigen 9]
• Other Product Names: [Receptor-binding cancer antigen expressed on SiSo cells; Receptor-binding cancer antigen expressed on SiSo cells; receptor-binding cancer antigen expressed on SiSo cells; estrogen receptor binding site associated antigen 9; Cancer-associated surface antigen RCAS1; Estrogen receptor-binding fragment-associated gene 9 protein]
• NCBI GI Number: 8928283
• NCBI Accession Number: O00559.1
• Uniprot Accession Number: O00559