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Cyclin B2

CAT: 0544-MBS4381379-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381379-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[CCNB2]
NCBI Gene ID
9133
Reactivity
Mouse, Rat, Human, Xenopus laevis
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc1). The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/ cyclin B enzyme, and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.
Other Gene Names
[CCNB2; CCNB2; HsT17299]
Short Name
[Cyclin B2]
Other Product Names
[G2/mitotic-specific cyclin-B2; G2/mitotic-specific cyclin-B2; G2/mitotic-specific cyclin-B2; cyclin B2]
NCBI GI Number
5921731
NCBI Accession Number
O95067.1
Uniprot Accession Number
O95067

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Alternative Products

CatalogName
221964-01Cyclin A (Cyclin-A1, CCNA1, Cyclin A1, CyclinA1, Cyclin-A2, Cyclin-A, Cyclin A, CyclinA, CCNA2, CCN1, CCNA) discontinued
254004Cyclin A (CCN1, CCNA, Ccna2, CCNA2_HUMAN, Cyclin A2, Cyclin-A, Cyclin-A2)
E8ET1612-8Cyclin A1+ Cyclin A2
301337Cyclin E1 (Cyclin-E1)
C8452-08Cyclin A
C8452-06CCyclin A2 (Cyclin-A2, CCNA2, CCN1, Cyclin-A, CCNA)
124485CCNT1 (Cyclin T1, Cyclin-T1, CycT1, Cyclin-T)
301337-FITCCyclin E1 (Cyclin-E1) (FITC)
C8452-71BCyclin A1 (Cyclin-A1, CCNA1)
124473CCNA1 (Cyclin A1, Cyclin-A1)

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