Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker)

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker)

• Gene Name: [CALD1]
• NCBI Gene ID: 800
• Reactivity: Human, Rat
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120'150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70'80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
• Other Gene Names: [CALD1; CALD1; CDM; HCAD; LCAD; H-CAD; L-CAD; NAG22; CAD; CDM; CDM]
• Short Name: [Caldesmon, HMW]
• Other Product Names: [caldesmon isoform 2; Caldesmon; caldesmon; caldesmon 1]
• NCBI GI Number: 4826657
• NCBI Accession Number: NP_004333.1
• NCBI GB Accession Number: NP_004333.1
• Uniprot Accession Number: Q05682