Uroplakin 1B (Urothelial Differentiation Marker)

• Gene Name:

  [UPK1B]

• NCBI Gene ID:

  7348

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.

• Other Gene Names:

  [UPK1B; UPK1B; UPIB; UPK1; TSPAN20; TSPAN20; UP1b; Tspan-20; UPIb]

• Short Name:

  [Uroplakin 1B]

• Other Product Names:

  [uroplakin-1b; Uroplakin-1b; uroplakin-1b; uroplakin 1B; Tetraspanin-20; Tspan-20; Uroplakin Ib; UPIb]

• NCBI GI Number:

  49619237

• NCBI Accession Number:

  NP_008883

• NCBI GB Accession Number:

  NP_008883.2

• Uniprot Accession Number:

  O75841