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C1QA/Complement C1q A-Chain

CAT: 0544-MBS4381296-01Size: 0.02 mg (With BSA & Azide at 0.2mg/mL)Dry Ice: NoHazardous: No
CAT#:0544-MBS4381296-01Size:0.02 mg (With BSA & Azide at 0.2mg/mL)
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Gene Name
[C1QA]
NCBI Gene ID
712
Reactivity
Human
Storage Conditions
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
Other Gene Names
[C1QA; C1QA]
Short Name
[C1QA/Complement C1q A-Chain]
Other Product Names
[complement C1q subcomponent subunit A; Complement C1q subcomponent subunit A; complement C1q subcomponent subunit A; complement C1q A chain]
NCBI GI Number
7705753
NCBI Accession Number
NP_057075
NCBI GB Accession Number
NP_057075.1
Uniprot Accession Number
P02745

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