CD71/Transferrin Receptor (TFRC)

• Gene Name:

  [TFRC]

• NCBI Gene ID:

  7037

• Reactivity:

  Human

• Storage Conditions:

  Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

• Other Gene Names:

  [TFRC; TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46; TR; TfR; TfR1; Trfr; sTfR]

• Short Name:

  [CD71/Transferrin Receptor (TFRC)]

• Other Product Names:

  [transferrin receptor protein 1 isoform 1; Transferrin receptor protein 1; transferrin receptor protein 1; transferrin receptor; T9; p90]

• NCBI GI Number:

  189458819

• NCBI Accession Number:

  NP_001121620.1

• NCBI GB Accession Number:

  NP_001121620.1

• Uniprot Accession Number:

  P02786