RET Proto-oncogene

RET Proto-oncogene

• Gene Name: [RET]
• NCBI Gene ID: 5979
• Reactivity: Human
• Storage Conditions: Antibody with azide: store at 2 to 8 degree C.
  Antibody without azide: store at -20 to -80 degree C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: The Ret proto-oncogene is structurally related to the growing family of tyrosine kinase transmembrane receptors and is involved in GDNF signaling. RET expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuro-retina and the growing tips of the renal collecting ducts in developing kidney.Alterations in RETgene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung's disease.
• Other Gene Names: [RET; RET; PTC; MTC1; HSCR1; MEN2A; MEN2B; CDHF12; CDHR16; RET-ELE1; CDHF12; CDHR16; PTC; RET51]
• Short Name: [RET Proto-oncogene]
• Other Product Names: [proto-oncogene tyrosine-protein kinase receptor Ret isoform c; Proto-oncogene tyrosine-protein kinase receptor Ret; proto-oncogene tyrosine-protein kinase receptor Ret; ret proto-oncogene; Cadherin family member 12; Proto-oncogene c-Ret]
• NCBI GI Number: 10862701
• NCBI Accession Number: NP_065681.1
• NCBI GB Accession Number: NP_065681.1
• Uniprot Accession Number: P07949